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Explore national- and state-level data for hundreds of health, environmental and socioeconomic measures, including background information about each measure. Use features on this page to find measures; view subpopulations, trends and rankings; and download and share content.
United States Value:
Percentage of adults who reported using prescription drugs non-medically (including pain relievers, stimulants and sedatives) or illicit drugs (excluding cannabis) in the last 12 months
Percentage of adults with a college degree who reported using prescription drugs non-medically (including pain relievers, stimulants, sedatives) or illicit drugs (excluding cannabis) in the last 12 months
5.2% - 11.8%
11.9% - 14.3%
14.4% - 17.3%
17.4% - 21.4%
21.5% - 31.7%
No Data
US Value: 16.8 %
Top State(s): Vermont: 6.5 %
Bottom State(s): Nevada: 24.9 %
Definition: Percentage of adults who reported using prescription drugs non-medically (including pain relievers, stimulants and sedatives) or illicit drugs (excluding cannabis) in the last 12 months
Data Source and Years(s): Denver Health and Hospital Authority, Researched Abuse, Diversion and Addiction-Related Surveillance (RADARS®) System Survey of Non-Medical Use of Prescription Drugs Program, 2025
Suggested Citation: America's Health Rankings analysis of Denver Health and Hospital Authority, Researched Abuse, Diversion and Addiction-Related Surveillance (RADARS®) System Survey of Non-Medical Use of Prescription Drugs Program, United Health Foundation, AmericasHealthRankings.org, accessed 2026.
Using illicit drugs, including prescription drugs without a doctor's guidance, can be dangerous and have long-lasting consequences, although the specific effects vary depending on the type of drug. Common negative health outcomes of illicit drug use include asthma, aggression, brain damage, sleep issues and increased risk of contracting HIV. Additionally, substance abuse can lead to addiction — also called substance use disorder — which often requires lifelong management.
In 2022, there were more than 100,000 drug-related deaths in the United States, and more than 24.6 million people in the U.S. age 12 and older reported using an illicit drug (not including marijuana) in the past year. Between 2018-2019 and 2020-2021, emergency room visits for substance use disorder increased 42% among adults ages 18-34 and 38% among adults older than 35. In 2022, there were an estimated 7.7 million drug-related emergency department visits.
The health consequences of using illicit or prescription drugs without a doctor's guidance are costly to individuals and society. In 2007, it was estimated that illicit drug use cost the U.S. a total of $193 billion. The opioid epidemic alone cost the U.S. nearly $1.5 trillion in 2020.
According to America’s Health Rankings analysis, the prevalence of past-year non-medical drug use is higher among:
Non-medical drug use can be prevented and treated. The National Institute on Drug Abuse lists evidence-based strategies and effective, sustainable and scalable approaches to implementing substance abuse prevention programs. The Substance Abuse and Mental Health Services Administration (SAMHSA) also has evidence-based programs and resources for parents, schools and primary care doctors, many of them focusing on children and adolescents.
When prevention is no longer an option, there are research-based treatment programs. Effective treatment approaches the individual as a whole person, addressing environmental factors, behaviors and other aspects of health, and is often a lifelong process. SAMHSA’s treatment locator can help individuals find state-licensed providers specializing in substance use disorders.
Healthy People 2030 has several drug-related objectives, including reducing the proportion of adolescents who used any illicit drug in the past 30 days and reducing the proportion of adults who used any illicit drug in the past 30 days.
O’Jiaku-Okorie, Adaeze, Xianghua Yin, and Christine Lucas. “QuickStats: Rate of Emergency Department Visits for Substance Use Disorders Among Adults Aged ≥18 Years, by Age Group — National Hospital Ambulatory Medical Care Survey, United States, 2018–2019 and 2020–2021.” MMWR. Morbidity and Mortality Weekly Report 72, no. 39 (September 29, 2023): 1073. https://doi.org/10.15585/mmwr.mm7239a6.
Substance Abuse and Mental Health Services Administration. “Drug Abuse Warning Network (DAWN): Findings from Drug-Related Emergency Department Visits, 2022.” Rockville, MD: Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration, 2023. https://store.samhsa.gov/sites/default/files/pep23-07-03-001.pdf.
America’s Health Rankings builds on the work of the United Health Foundation to draw attention to public health and better understand the health of various populations. Our platform provides relevant information that policymakers, public health officials, advocates and leaders can use to effect change in their communities.
We have developed detailed analyses on the health of key populations in the country, including women and children, seniors and those who have served in the U.S. Armed Forces, in addition to a deep dive into health disparities across the country.
