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Drug Deaths
Drug Deaths in Arizona

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Arizona Value:


Number of deaths due to drug injury (unintentional, suicide, homicide or undetermined) per 100,000 population (1-year)

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Drug Deaths by State

Number of deaths due to drug injury (unintentional, suicide, homicide or undetermined) per 100,000 population (1-year)

Drug Deaths Trends

Number of deaths due to drug injury (unintentional, suicide, homicide or undetermined) per 100,000 population (1-year)

Trend: Drug Deaths in Arizona, United States, 2023 Annual Report

Number of deaths due to drug injury (unintentional, suicide, homicide or undetermined) per 100,000 population (1-year)

United States

 CDC WONDER, Multiple Cause of Death Files

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About Drug Deaths

US Value: 32.1

Top State(s): Nebraska: 11.3

Bottom State(s): West Virginia: 87.1

Definition: Number of deaths due to drug injury (unintentional, suicide, homicide or undetermined) per 100,000 population (1-year)

Data Source and Years: CDC WONDER, Multiple Cause of Death Files, 2021

Suggested Citation: America's Health Rankings analysis of CDC WONDER, Multiple Cause of Death Files, United Health Foundation,, accessed 2023.

Deaths resulting from drug overdose burden individuals, families, their communities, the health care system and the economy. Drug overdoses are a leading cause of injury death and have increased dramatically in recent years. 

More than 1 million Americans have died from drug overdose since 1999. There were more than 106,699 confirmed drug overdose deaths in the United States in 2021 alone, more than 80,000 of which involved an opioid. 

Studies have found that increases in overdose deaths are associated with increases in child maltreatment reports and foster care placements. In 2017, fatal opioid overdoses and opioid use disorder cost the United States $1.02 trillion.

Those who take a high daily dosage of prescription pain relievers (e.g., methadone, oxycodone or hydrocodone) are vulnerable to abuse of prescription opioids and overdose.

According to America’s Health Rankings data, populations with higher drug overdose death rates include:

  • Men, who have a drug overdose death rate twice that of women.
  • Adults ages 35-44, who have the highest rate of drug overdose deaths compared with all other age groups. 
  • American Indian/Alaska Native, white and Black adults compared with Asian adults.
  • Urban residents compared with rural residents. The disparity is especially large among males in urban counties, who have an overdose rate 18% higher than males in rural counties.

Additional studies have found that drug deaths are highest among individuals working in construction and extraction occupations.

Opioid overdoses may be reversed with naloxone, an opioid antagonist. Strategies to prevent overdose deaths and reduce harm among those with opioid addiction include:

For health care providers, the Centers for Disease Control and Prevention has developed the Guideline for Prescribing Opioids for Chronic Pain and a prescription checklist to encourage safe prescribing practices. 

Individuals can work with their doctors to safely and effectively manage their pain and avoid the risk of opioid abuse. The Substance Abuse and Mental Health Services Administration offers resources and advice about what to do if someone you know has a problem with drugs.

Reducing drug overdose deaths is a Healthy People 2030 leading health indicator.

Billock, Rachael M. “QuickStats: Age-Adjusted Drug Overdose Death Rates Among Workers Aged 16–64 Years in Usual Occupation Groups with the Highest Drug Overdose Death Rates — National Vital Statistics System, United States, 2020.” MMWR. Morbidity and Mortality Weekly Report 71, no. 29 (July 22, 2022): 948.

Crowley, Daniel Max, Christian M. Connell, Damon Jones, and Michael W. Donovan. “Considering the Child Welfare System Burden from Opioid Misuse: Research Priorities for Estimating Public Costs.” The American Journal of Managed Care 25, no. 13 Suppl (2019): S256–63.

Dowell, Deborah, Kathleen R. Ragan, Christopher M. Jones, Grant T. Baldwin, and Roger Chou. “CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022.” MMWR. Recommendations and Reports 71, no. 3 (November 4, 2022): 1–95.

Gladden, R. Matthew, Pedro Martinez, and Puja Seth. “Fentanyl Law Enforcement Submissions and Increases in Synthetic Opioid–Involved Overdose Deaths — 27 States, 2013–2014.” MMWR. Morbidity and Mortality Weekly Report 65, no. 33 (August 26, 2016): 837–43.

Rudd, Rose A., Puja Seth, Felicita David, and Lawrence Scholl. “Increases in Drug and Opioid-Involved Overdose Deaths — United States, 2010–2015.” MMWR. Morbidity and Mortality Weekly Report 65, no. 5051 (December 30, 2016): 1445–52.

Spencer, Merianne Rose, Matthew Garnett, and Arialdi M. Miniño. “Urban–Rural Differences in Drug Overdose Death Rates, 2020.” Hyattsville, MD: National Center for Health Statistics, July 21, 2022.

Zibbell, Jon E., Arnie Aldridge, Megan Grabenauer, David Heller, Sarah Duhart Clarke, DeMia Pressley, and Hope Smiley McDonald. “Associations between Opioid Overdose Deaths and Drugs Confiscated by Law Enforcement and Submitted to Crime Laboratories for Analysis, United States, 2014–2019: An Observational Study.” The Lancet Regional Health - Americas 25 (September 2023): 100569.

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